2-Methoxy-4-nitrobenzoic acid

CAS NO.：2597-56-0
Empirical Formula: C8H7NO5
Molecular Weight: 197.14
MDL number: MFCD00216573
EINECS: 219-998-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-Methoxy-4-nitrobenzoic acid?

Chemical properties

White to Off-White Crystalline Solid

The Uses of 2-Methoxy-4-nitrobenzoic acid

2-Methoxy-4-nitrobenzoic Acid (cas# 2597-56-0) is a compound useful in organic synthesis.

The Uses of 2-Methoxy-4-nitrobenzoic acid

2-Methoxy-4-nitrobenzoic acid may be used as a starting material in the following syntheses:

2-Methoxy-4-nitrobenzamide, a nitroamide derivative.
4-Amino-2-methoxybenzamide, an aminobenzamide derivative.
N,2-Dimethoxy-N-methyl-4-nitrobenzamide, a Weinreb amide derivative.
1-(2-Methoxy-4-nitrophenyl)-5-methylhex-2-yn-1-one, a ynone derivative.
2,5-Constrained piperidine derivative, a potential CCR3 (Chemokine (C-C Motif) Receptor 3) antagonist.

General Description

2-Methoxy-4-nitrobenzoic acid is an alkoxybenzoic acid derivative. It has been reported to be synthesized by reacting 2-hydroxy-4-nitrobenzoic acid with methyl iodide and characterized by ¹H and ¹³C-NMR spectra.

Properties of 2-Methoxy-4-nitrobenzoic acid

Melting point:	146-148 °C (lit.)
Boiling point:	390.9±27.0 °C(Predicted)
Density	1.430±0.06 g/cm3(Predicted)
solubility	Acetic Acid, Methanol
form	Solid
pka	3.13±0.13(Predicted)
color	White to Off-White
CAS DataBase Reference	2597-56-0(CAS DataBase Reference)

Safety information for 2-Methoxy-4-nitrobenzoic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.