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HomeProduct name list2'-MECCPA

2'-MECCPA

2'-MECCPA Structural

What is 2'-MECCPA?

The Uses of 2'-MECCPA

2''-?MeCCPA is an inhibitor of forskolin-stimulated adenylyl cyclase. It is also a selective A1 adenosine receptor agonist.

What are the applications of Application

2′-MeCCPA is a potent and highly selective agonist at Adenosine A1-R

Definition

ChEBI: 2-[2-chloro-6-(cyclopentylamino)-9-purinyl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol is a purine nucleoside.

Biological Activity

Potent and highly selective agonist at A 1 adenosine receptors (K i values are 3.3, 9580, 37600 and 1150 nM for human recombinant A 1 , A 2A , A 2B and A 3 receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat cortical membranes with an IC 50 value of 13.1 nM.

storage

Store at +4°C

Properties of 2'-MECCPA

Boiling point: 643.3±65.0 °C(Predicted)
Density  1.76±0.1 g/cm3(Predicted)
storage temp.  Store at +4°C
solubility  Soluble to 25 mM in DMSO
form  Powder
pka 13.13±0.70(Predicted)
color  Off-white to light yellow

Safety information for 2'-MECCPA

Computed Descriptors for 2'-MECCPA

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