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HomeProduct name listN6-CYCLOPENTYLADENOSINE

N6-CYCLOPENTYLADENOSINE

Synonym(s):CPA

N6-CYCLOPENTYLADENOSINE Structural

What is N6-CYCLOPENTYLADENOSINE?

The Uses of N6-CYCLOPENTYLADENOSINE

N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist with Ki values of 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively and EC50 value of 18600 nM for hA2B. It has also shown its efficacy against organophosphate toxcity.

The Uses of N6-CYCLOPENTYLADENOSINE

N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.

What are the applications of Application

N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist

Biological Activity

Potent and selective adenosine A 1 receptor agonist (K i values are 2.3, 790 and 43 nM for human A 1 , A 2A and A 3 receptors respectively; EC 50 = 18600 nM for hA 2B ). Centrally active following systemic administration in vivo .

Biochem/physiol Actions

N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.

storage

Desiccate at +4°C

Properties of N6-CYCLOPENTYLADENOSINE

Melting point: 78.8 °C
Boiling point: 673.4±65.0 °C(Predicted)
Density  1.78±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  H2O: soluble1.7mg/mL
form  solid
pka 13.12±0.70(Predicted)
color  white to off-white

Safety information for N6-CYCLOPENTYLADENOSINE

Computed Descriptors for N6-CYCLOPENTYLADENOSINE

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