N6-CYCLOPENTYLADENOSINE
Synonym(s):CPA
- CAS NO.:41552-82-3
- Empirical Formula: C15H21N5O4
- Molecular Weight: 335.36
- MDL number: MFCD00036845
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 21:11:14
What is N6-CYCLOPENTYLADENOSINE?
The Uses of N6-CYCLOPENTYLADENOSINE
N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist with Ki values of 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively and EC50 value of 18600 nM for hA2B. It has also shown its efficacy against organophosphate toxcity.
The Uses of N6-CYCLOPENTYLADENOSINE
N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.
What are the applications of Application
N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist
Biological Activity
Potent and selective adenosine A 1 receptor agonist (K i values are 2.3, 790 and 43 nM for human A 1 , A 2A and A 3 receptors respectively; EC 50 = 18600 nM for hA 2B ). Centrally active following systemic administration in vivo .
Biochem/physiol Actions
N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.
storage
Desiccate at +4°C
Properties of N6-CYCLOPENTYLADENOSINE
Melting point: | 78.8 °C |
Boiling point: | 673.4±65.0 °C(Predicted) |
Density | 1.78±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | H2O: soluble1.7mg/mL |
form | solid |
pka | 13.12±0.70(Predicted) |
color | white to off-white |
Safety information for N6-CYCLOPENTYLADENOSINE
Computed Descriptors for N6-CYCLOPENTYLADENOSINE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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