2-Ethylhexyl salicylate

Absorption

Intended for local use only, no systemic absorption.

Toxicity

LD50, (oral, rat): > 5000 mg/Kg. LD50 (dermal, rabbit): > 5000 mg/Kg.

Chemical properties

liquid

Occurrence

Has apparently not been reported to occur in nature.

The Uses of 2-Ethylhexyl salicylate

2-ethylhexyl salicylate is also known as ethylhexyl salicylate and octyl salicylate. It is a uVB absorber.

The Uses of 2-Ethylhexyl salicylate

Solvent for solid sunscreens.

The Uses of 2-Ethylhexyl salicylate

ethylhexyl salicylate is an FDA-approved uVB sunscreen chemical, it absorbs within the entire uVB range. It has an approved usage level of 3 to 5 percent in both the united States and the european union, and is a good solubilizer for benzophenone-3. In suntan lotions, it is used as a preservative and anti-microbial. This is a salt of salicylic acid occurring in wintergreen leaves and in other plants. It is also synthetically manufactured. It is considered a non-comedogenic raw material. This is the InCI name for octyl salicylate.

The Uses of 2-Ethylhexyl salicylate

octisalate is a uVB protector. This is the drug name for ethylhexyl salicylate and octyl salicylate.

Background

Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters. Octyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm.
It is an ester of salicylic acid and 2-ethylhexanol. The salicylate portion of the molecule absorbs ultraviolet light to protect skin from the harmful effects of exposure to sunlight, while the ethylhexanol portion functions as an emollient.

Indications

Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.

What are the applications of Application

Octyl salicylate is a fragrance ingredient that blocks UVB rays

Preparation

From 2-ethylhexanol and salicylic acid by azeotropic-type esterification (Arctander, 1969).

Definition

ChEBI: Ethylhexyl salicylate is a benzoate ester and a member of phenols. It is functionally related to a salicylic acid.

brand name

Escalol (ISP Van Dyk); Neo Heliopan (Haarmann & Reimer, Germany); Uvinul (BASF). Note—The International Cosmetic Ingredient (INCI) name for octisalate is octyl salicylate.

General Description

2-Ethylhexyl salicylate(EHS) is an organic ultraviolet(UV) absorber that can be used as a photostable ingredient in cosmetic formulations. It shows an absorption spectra in the range of 280-320 nm in the UV region.

Flammability and Explosibility

Non flammable

Pharmacokinetics

Data not found.

Metabolism

Intended for local use only, no systemic absorption.