2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Synonym(s):2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-benzoic acid;GSK 650394;GSK650394
- CAS NO.：890842-28-1
- Empirical Formula: C25H22N2O2
- Molecular Weight: 382.45
- MDL number: MFCD12828779
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 11:39:26
![2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Structural](https://img.chemicalbook.in/CAS/20180713/GIF/890842-28-1.gif)
What is 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid?
The Uses of 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.
What are the applications of Application
GSK 650394 is an SGK1 inhibitor used in prostate cancer research
Definition
ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine.
Biochem/physiol Actions
GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.
storage
Store at RT
Properties of 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
| storage temp. | room temp |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
Safety information for 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Computed Descriptors for 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
New Products
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