2-Cyanobenzaldehyde

CAS NO.：7468-67-9
Empirical Formula: C8H5NO
Molecular Weight: 131.13
MDL number: MFCD00017503
EINECS: 203-267-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-25 18:17:30

What is 2-Cyanobenzaldehyde?

Chemical properties

white to orange to beige powder, crystals and/or

The Uses of 2-Cyanobenzaldehyde

2-Cyanobenzaldehyde may be used:

in the base-catalyzed one-pot synthesis of 3-substituted isoindolinones
in the synthesis of 3-oxo-2,3-dihydro-1H-isoindoles, via Baylis-Hillman reaction
in the synthesis of 3-(N-substituted amino)-1-isoindolenones

The Uses of 2-Cyanobenzaldehyde

This compound can act as a crosslinker to protein kinase, which is responsible for thousands of phosphorylation events in the phosphoproteome.

What are the applications of Application

2-Cyanobenzaldehyde is used in the base-catalyzed one-pot synthesis of 3-substituted isoindolinones

General Description

Aldol addition of enolizable 1,3-dicarbonyl compounds to 2-cyanobenzaldehyde in the presence of a tertiary amine has been reported. Biotransformation of 2-cyanobenzaldehyde by Euglena gracilis Z cultured photohetero-trophically has been reported.

Properties of 2-Cyanobenzaldehyde

Melting point:	103-105 °C (lit.)
Boiling point:	284.9±23.0 °C(Predicted)
Density	1.15±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly, Sonicated), Chloroform (Slightly)
form	Powder, Crystals and/or Chunks
color	White to orange to beige
Sensitive	Air Sensitive
CAS DataBase Reference	7468-67-9(CAS DataBase Reference)
NIST Chemistry Reference	2-Cyanobenzaldehyde(7468-67-9)

Safety information for 2-Cyanobenzaldehyde

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.