2-Chloro-4-nitrotoluene

Synonym(s):2-Chloro-1-methyl-4-nitrobenzene

CAS NO.：121-86-8
Empirical Formula: C7H6ClNO2
Molecular Weight: 171.58
MDL number: MFCD00007210
EINECS: 204-501-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-10-21 08:47:24

What is 2-Chloro-4-nitrotoluene?

Chemical properties

LIGHT YELLOW CRYSTALLINE POWDER

The Uses of 2-Chloro-4-nitrotoluene

2-Chloro-4-nitrotoluene is a substituted toluene used in the preparation of wide range of compounds such as herbicides, analgesics and

What are the applications of Application

2-Chloro-4-nitrotoluene is a substituted toluene

Definition

ChEBI: 2-chloro-4-nitrotoluene is a nitrotoluene that is p-nitrotoluene in which one of the hydrogens that is ortho to the methyl group has been replaced by a chlorine. A pale yellow crystalline compound that is insoluble in water but dissolves in most organic solvents, it is used in the manufacture of dyes. It is a member of monochlorobenzenes and a nitrotoluene.

Production Methods

Chlorination of 4-nitrotoluene at 50 ℃ in the presence of iron(III) chloride catalyst gives good conversion to 2-chloro-4-nitrotoluene, the most readily obtained of all the chloronitrotoluene isomers.

Synthesis Reference(s)

Journal of the American Chemical Society, 104, p. 4680, 1982 DOI: 10.1021/ja00381a032

Safety Profile

A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx and Cl-.

Properties of 2-Chloro-4-nitrotoluene

Melting point:	61 °C
Boiling point:	260 °C
Density	1.3246 (rough estimate)
refractive index	1.5470 (estimate)
Flash point:	150 °C
storage temp.	Sealed in dry,Room Temperature
solubility	acetonitrile: soluble
form	neat
color	Pale Yellow
Water Solubility	49 mg/L (20 ºC)
BRN	1817924
CAS DataBase Reference	121-86-8(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 2-chloro-1-methyl-4-nitro-(121-86-8)
EPA Substance Registry System	2-Chloro-4-nitrotoluene (121-86-8)

Safety information for 2-Chloro-4-nitrotoluene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H320:Serious eye damage/eye irritation H401:Hazardous to the aquatic environment, acute hazard H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P321:Specific treatment (see … on this label). P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P501:Dispose of contents/container to..…