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HomeProduct name list2-Chloro-4-methoxypyridine

2-Chloro-4-methoxypyridine

  • CAS NO.:17228-69-2
  • Empirical Formula: C6H6ClNO
  • Molecular Weight: 143.57
  • MDL number: MFCD02093951
  • EINECS: 625-435-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
2-Chloro-4-methoxypyridine Structural

What is 2-Chloro-4-methoxypyridine?

Chemical properties

Colorless liquid

The Uses of 2-Chloro-4-methoxypyridine

2-Chloro-4-methoxypyridine may be used to synthesize:

  • 2-(2′,4′-difluorophenyl)-4-methoxypyridine
  • (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl)pyrimidin-4-yl]methanol
  • (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl) pyrimidin-4-yl]methyl acetate

The Uses of 2-Chloro-4-methoxypyridine

It is an active pharmaceutical ingredient.

General Description

2-Chloro-4-methoxypyridine can be obtained from the reaction between 2-chloro-4-nitropyridine and sodium methoxide in the presence of dioxane. It can also be prepared starting from 4-methoxy-2(1H)-pyridone and 4-nitropyridine N-oxide.

Properties of 2-Chloro-4-methoxypyridine

Boiling point: 224-225 °C (lit.)
Density  1.258 g/mL at 25 °C (lit.)
refractive index  n20/D 1.5400(lit.)
Flash point: >230 °F
storage temp.  Inert atmosphere,Room Temperature
solubility  Soluble in alcohol.
form  Liquid
pka 2.25±0.10(Predicted)
Specific Gravity 1.258
color  Colorless to pale yellow
BRN  1423379
CAS DataBase Reference 17228-69-2(CAS DataBase Reference)

Safety information for 2-Chloro-4-methoxypyridine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Chloro-4-methoxypyridine

InChIKey PMTPFBWHUOWTNN-UHFFFAOYSA-N

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