2-Chloro-1,3-dinitrobenzene

CAS NO.：606-21-3
Empirical Formula: C6H3ClN2O4
Molecular Weight: 202.55
MDL number: MFCD00014689
EINECS: 210-107-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-Chloro-1,3-dinitrobenzene?

Chemical properties

Yellow crystals. Soluble in ethanol, ether, and toluene

The Uses of 2-Chloro-1,3-dinitrobenzene

2-Chloro-1,3-dinitrobenzene can be used as intermediates of dyes and pigments. Also used as solvents in HPLC, NMR.

The Uses of 2-Chloro-1,3-dinitrobenzene

The commercial mixture of chlorodinitrobenzenes is used to synthesize other compounds.

The Uses of 2-Chloro-1,3-dinitrobenzene

2,6-Dinitrochlorobenzene (2-Chloro-1,3-dinitrobenzene) is a thiol-modifying agent.

Hazard

Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure. Very toxic to aquatic life with long lasting effects.

Synthesis

The synthesis of 2-Chloro-1,3-dinitrobenzene is as follows:
Add 800ml of sulfolane as solvent to a 2L flask, then add 246.5g of 3,5-dinitro-4-chlorobenzoic acid and 168g of sodium bicarbonate,Heat to 195°C to react for 2h. After the reaction is complete, cool to 130°C and distill under reduced pressure.The product 2-Chloro-1,3-dinitrobenzene, 178.4g, was obtained by rectification with a yield of 88.1%.
synthesis of 2-Chloro-1,3-dinitrobenzene.png

Properties of 2-Chloro-1,3-dinitrobenzene

Melting point:	86-88°C
Boiling point:	315°C
Density	1,687 g/cm³
refractive index	1.5870 (estimate)
Flash point:	315°C
storage temp.	2-8°C
form	solid
color	Pale-yellow to Yellow-brown
Water Solubility	Soluble in alcohol. Moderately soluble in benzene, ether. Practically insoluble in water.
Merck	14,2137
BRN	522187
CAS DataBase Reference	606-21-3(CAS DataBase Reference)
NIST Chemistry Reference	1-Chloro-2,6-dinitrobenzene(606-21-3)
EPA Substance Registry System	2,6-Dinitrochlorobenzene (606-21-3)

Safety information for 2-Chloro-1,3-dinitrobenzene

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H300:Acute toxicity,oral H310:Acute toxicity,dermal H330:Acute toxicity,inhalation H373:Specific target organ toxicity, repeated exposure H400:Hazardous to the aquatic environment, acute hazard H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P320:Specific treatment is urgent (see … on this label). P330:Rinse mouth. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up.