2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

CAS NO.：43229-01-2
Empirical Formula: C15H12BrNO4
Molecular Weight: 350.16
MDL number: MFCD06797599
EINECS: 610-115-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-14 20:16:46

What is 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone?

The Uses of 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone, can be used as an intermediate in the synthesis of Arformoterol Tartrate (A767505), which is a derivative of Arformoterol, a long acting beta-adrenoceptor agonist drug indicated for the treatment of chronic obstructive pulmonary disease (COPD).

Properties of 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Melting point:	135-137 °C(Solv: ethanol (64-17-5))
Boiling point:	465.2±35.0 °C(Predicted)
Density	1.517±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Soluble in Methylene chloride, sparingly soluble in ethyl acetate, insoluble in water
form	Solid
color	Pale yellow to cream coloured crystalline powder
CAS DataBase Reference	43229-01-2(CAS DataBase Reference)

Safety information for 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.