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HomeProduct name list2-Azetidinone

2-Azetidinone

Synonym(s):β-Propiolactam;2-Azacyclobutanone

2-Azetidinone Structural

What is 2-Azetidinone?

The Uses of 2-Azetidinone

2-Azetidinone was used in synthesis of optically pure densely functionalized γ-lactams.

What are the applications of Application

2-Azetidinone is an unsubstituted four membered lactam

Definition

ChEBI: An unsubstituted beta-lactam compound.

General Description

2-Azetidinone is an unsubstituted four membered lactam. 2-Azetidinone is the fundamental building block of β-lactam antibiotics. X-ray photoelectron spectra of 2-azetidinone was investigated. 2-Azetidinone undergoes hydrolysis with aqueous alkali to yield β-alanine.

Properties of 2-Azetidinone

Melting point: 74-76 °C (lit.)
Boiling point: 106 °C/15 mmHg (lit.)
Density  1.0347 (rough estimate)
refractive index  1.4035 (estimate)
storage temp.  2-8°C
solubility  chloroform: very soluble(lit.)
form  Liquid
pka 15.86±0.20(Predicted)
color  Clear
BRN  104563
InChI InChI=1S/C3H5NO/c5-3-1-2-4-3/h1-2H2,(H,4,5)
CAS DataBase Reference 930-21-2(CAS DataBase Reference)

Safety information for 2-Azetidinone

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Azetidinone

InChIKey MNFORVFSTILPAW-UHFFFAOYSA-N
SMILES N1CCC1=O

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