2-Butanone oxime

Synonym(s):Methyl ethyl ketoxime

CAS NO.：96-29-7
Empirical Formula: C4H9NO
Molecular Weight: 87.12
MDL number: MFCD00013935
EINECS: 406-930-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-03 16:24:09

What is 2-Butanone oxime?

Chemical properties

2-Butanone oxime is a colorless or light yellow oily transparent liquid that has strong complexation with metal ions and is volatile in the air. It can react with hydrochloric acid and sulfuric acid to form methyl ethyl ketone.

The Uses of 2-Butanone oxime

2-Butanone oxime was employed as reagent and solvent in the syntheses of ketoimine and 2,4-dipyridyl-1,3,5-triazapentadiene palladium(II) complexes. It was also used in the synthesis of novel acetaldiimine cobalt complex, [CoI2{((CH3CH2)(CH3)C=NO)2C(CH3)2}]. Methyl ethyl ketoxime is used primarily as an antiskinning agent in alkyd coating resins

What are the applications of Application

2-Butanone oxime is a reagent and solvent

Preparation

2-Butanone oxime is obtained by the reaction of butanone and hydroxylamine hydrochloride. It can also be synthesized by the reaction between butanone and hydroxylamine sulfate.

General Description

Clear colorless liquid with a musty odor.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

2-Butanone oxime is sensitive to heat. Has exploded at least twice when heated in the presence of acidic impurities [Chem. Eng. News, 1974, 52(35), 3]. Reacts with oxidizing agents. Mixtures with strong acids may explode. Reacts with sulfuric acid to form an explosive product .

Fire Hazard

2-Butanone oxime is combustible.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intraperitoneal route. Moderately toxic by subcutaneous route. May explode if heated. Reacts with sulfuric acid to form an explosive product. When heated to decomposition it emits toxic fumes of NOX.

Properties and Applications

TEST ITEMS	SPECIFICATION
APPEARANCE	COLORLESS TRANSPARENT CLEAR OILY LIQUID,FLAMMABLE
GRADE	EXCELLENT GRADE
MEKO CONTENT	99.7%min
WATER CONTENT	0.04%
ACID NUMBER (KOH mg/g)	0.05 max
CHROMA NO. (PLATINUM-COBALT)	2 max

Properties of 2-Butanone oxime

Melting point:	-30 °C
Boiling point:	59-60 °C15 mm Hg(lit.)
Density	0.924 g/mL at 25 °C(lit.)
vapor density	3 (vs air)
vapor pressure	<8 mm Hg ( 20 °C)
refractive index	n20/D 1.442(lit.)
Flash point:	140 °F
solubility	water: soluble100g/L at 25°C
form	Liquid
pka	pK1:12.45 (25°C)
color	Clear colorless to pale yellow
Water Solubility	114 g/L (20 ºC)
BRN	1698241
Dielectric constant	3.4（20℃）
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents. May react with strong acids to form an explosive material.
CAS DataBase Reference	96-29-7(CAS DataBase Reference)
NIST Chemistry Reference	2-Butanone, oxime(96-29-7)
EPA Substance Registry System	Methyl ethyl ketoxime (96-29-7)

Safety information for 2-Butanone oxime

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H301:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H336:Specific target organ toxicity,single exposure; Narcotic effects H350:Carcinogenicity H370:Specific target organ toxicity, single exposure H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.