2-(Aminomethyl)-1-Boc-piperidine

CAS NO.：370069-31-1
Empirical Formula: C11H22N2O2
Molecular Weight: 214.3
MDL number: MFCD01317791
SAFETY DATA SHEET (SDS)
Update Date: 2023-10-19 12:00:42

What is 2-(Aminomethyl)-1-Boc-piperidine?

Chemical properties

White powder

The Uses of 2-(Aminomethyl)-1-Boc-piperidine

Reactant for synthesis of: TRPV1 antagonists, CHK1 inhibitors, p38a MAP kinase inhibitors, Carbamoylphosphonates, Macrolactams via carbonylation/intramolecular amidation, Intramolecular transamidation.

The Uses of 2-(Aminomethyl)-1-Boc-piperidine

Reactant for synthesis of:
TRPV1 antagonists
CHK1 inhibitors
p38a MAP kinase inhibitors
Carbamoylphosphonates
Macrolactams via carbonylation/intramolecular amidation
Intramolecular transamidation

Reactions

2-(Aminomethyl)-1-Boc-piperidine, also known as Tert-butyl 2-(aminomethyl)piperidine-1-carboxylate, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as tert-butyl 2 - ((2, 6 - dimethyl-phenyl amide) methyl) piperidine -1 - carboxylic esters which can be used for preparing medicines in the fields of local anaesthesia or analgesia.
2-(Aminomethyl)-1-Boc-piperidine

Properties of 2-(Aminomethyl)-1-Boc-piperidine

Boiling point:	299.4±13.0 °C(Predicted)
Density	1.0124 g/mL at 25 °C
refractive index	n20/D 1.4745
Flash point:	110 °C
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Soluble in DMSO.
pka	10.32±0.29(Predicted)
CAS DataBase Reference	370069-31-1(CAS DataBase Reference)

Safety information for 2-(Aminomethyl)-1-Boc-piperidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.