2-amino-4-phosphonobutyric acid
- CAS NO.：6323-99-5
- Empirical Formula: C4H10NO5P
- Molecular Weight: 183.1
- MDL number: MFCD00013999
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is 2-amino-4-phosphonobutyric acid?
Description
DL-AP4 is a broad-spectrum glutamatergic antagonist. DL-AP4 (2.5 mM) inhibits electrically stimulated synaptic transmission in rabbit hippocampal slices. It also depresses depolarizations induced by NMDA , L-homocysteate, or kainate in isolated frog spinal cord when used at a concentration of 1 mM. DL-AP4 (0.2 mM) inhibits the accumulation of inositol induced by ibotenate , quisqualate, L-glutamate, and L-aspartate in rat hippocampal slices.
The Uses of 2-amino-4-phosphonobutyric acid
DL-2-Amino-4-phosphonobutanoic acid (AP4) is an amino-acid derivative reported to block cone signals in the rat retina. Improves learning and memory processes in passive and active avoidance situations in rats.
storage
Store at RT
Properties of 2-amino-4-phosphonobutyric acid
| Melting point: | 229-231 °C(Solv: ethanol (64-17-5); water (7732-18-5)) |
| Boiling point: | 491.7±55.0 °C(Predicted) |
| Density | 1.628±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Water:9.15(Max Conc. mg/mL);50.0(Max Conc. mM) |
| form | White solid. |
| pka | 2.19±0.10(Predicted) |
| Water Solubility | Soluble to 50 mM in water |
Safety information for 2-amino-4-phosphonobutyric acid
Computed Descriptors for 2-amino-4-phosphonobutyric acid
New Products
Tubulysin D Tubulysin E Tubulysin F 2,2-diethoxyethanethioamide 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 2H-Pyran, 4-ethynyltetrahydro- tetrahydro-4-methyl-2H-pyran 1-(1,1-Difluoroethyl)-2-fluorobenzene 3-Aminocyclobutanone hydrochloride 2,2-Difluoropropanol Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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