2-Amino-4-chloropyrimidine

CAS NO.：3993-78-0
Empirical Formula: C4H4ClN3
Molecular Weight: 129.55
MDL number: MFCD00038021
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-Amino-4-chloropyrimidine?

Chemical properties

White Solid

The Uses of 2-Amino-4-chloropyrimidine

2-Amino-4-chloropyrimidine is a substrate used in a palladium-catalyzed cyanation with zinc(II) cyanide. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Purification Methods

It has also been purified by sublimation in a vacuum and recrystrallisation from H2O. [Hilbert & Johnson J Am Chem Soc 52 1155 1930, Beilstein 24 H 80, 25 III/IV 2117.]

Properties of 2-Amino-4-chloropyrimidine

Melting point:	155-160 °C (dec.)
Boiling point:	314.6±34.0 °C(Predicted)
Density	1.437±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in dimethyl sulfoxide.
form	Solid
pka	3.55±0.10(Predicted)
color	White
CAS DataBase Reference	3993-78-0(CAS DataBase Reference)

Safety information for 2-Amino-4-chloropyrimidine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.