2-Amino-3-bromo-5-methylpyridine

CAS NO.：17282-00-7
Empirical Formula: C6H7BrN2
Molecular Weight: 187.04
MDL number: MFCD00068231
EINECS: 626-356-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-08 13:48:25

What is 2-Amino-3-bromo-5-methylpyridine?

Chemical properties

Light yellow Cryst

The Uses of 2-Amino-3-bromo-5-methylpyridine

2-Amino-3-bromo-5-methylpyridine is used for the preparation of imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrazines, imidazo[1,2-c]pyrimidines, and imidazo[1,2-d]triazines as JNK and ERK kinase inhibitors

The Uses of 2-Amino-3-bromo-5-methylpyridine

2-Amino-3-bromo-5-methylpyridine may be used in the synthesis of:

3-bromo-2-chloro-5-methylpyridine
3-bromo-2-fluoro-5-methylpyridine
8-methyl-1,2,3,5-tetrahydropyrido[3,4-b][1,4]diazepin-4-one
3-bromo-2-(ethylamino)-5-methylpyridine
(3-bromo-5-methylpyridin-2-yl)aniline
5-methyl-3-(phenylethynyl)pyridin-2-amine
3-[(2-methoxyphenyl)ethynyl]-5-methylpyridin-2-amine
3-[(4-methoxyphenyl)ethynyl]-5-methylpyridin-2-amine
3-[(3-chlorophenyl)ethynyl]-5-methylpyridin-2-amine

Properties of 2-Amino-3-bromo-5-methylpyridine

Melting point:	73-76 °C (lit.)
Boiling point:	252.3±35.0 °C(Predicted)
Density	1.5672 (rough estimate)
refractive index	1.5500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Crystalline Powder
pka	4.28±0.49(Predicted)
color	Yellow to beige or brown
Water Solubility	Insoluble
BRN	471829
CAS DataBase Reference	17282-00-7(CAS DataBase Reference)
NIST Chemistry Reference	2-Amino-3-bromo-5-methylpyridine(17282-00-7)

Safety information for 2-Amino-3-bromo-5-methylpyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.