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HomeProduct name list2-Amino-5-methylpyridine

2-Amino-5-methylpyridine

Synonym(s):2-Amino-5-picoline;6-Amino-3-picoline

  • CAS NO.:1603-41-4
  • Empirical Formula: C6H8N2
  • Molecular Weight: 108.14
  • MDL number: MFCD00006328
  • EINECS: 216-503-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-09-25 17:15:13
2-Amino-5-methylpyridine Structural

What is 2-Amino-5-methylpyridine?

Chemical properties

light yellow crystalline flakes

The Uses of 2-Amino-5-methylpyridine

Intermediate.

What are the applications of Application

2-Amino-5-methylpyridine is a pharmaceutical intermediate compound used in the preparation of Abametapir, a prescription drug used to treat head lice infestations in people 6 months of age and older.

Safety Profile

Poison by ingestion,subcutaneous, and skin contact routes. When heated todecomposition it emits toxic vapors of NOx.

Purification Methods

Crystallise it from acetone. [Beilstein 22/9 V 289.]

Properties of 2-Amino-5-methylpyridine

Melting point: 76-77 °C(lit.)
Boiling point: 227 °C(lit.)
Density  227
vapor pressure  3.706Pa at 25℃
refractive index  1,524-1,528
Flash point: 118°C
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  1000g/l
form  Crystalline Powder, Crystals or Flakes
pka pK1: 7.22(+1) (25°C)
color  White to light yellow
Sensitive  Hygroscopic
BRN  107050
CAS DataBase Reference 1603-41-4(CAS DataBase Reference)
NIST Chemistry Reference 2-Pyridinamine, 5-methyl-(1603-41-4)
EPA Substance Registry System 6-Amino-3-picoline (1603-41-4)

Safety information for 2-Amino-5-methylpyridine

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Amino-5-methylpyridine

InChIKey CMBSSVKZOPZBKW-UHFFFAOYSA-N

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