2-Amino-5-methylpyridine

Synonym(s):2-Amino-5-picoline;6-Amino-3-picoline

CAS NO.：1603-41-4
Empirical Formula: C6H8N2
Molecular Weight: 108.14
MDL number: MFCD00006328
EINECS: 216-503-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-09-27 09:06:03

What is 2-Amino-5-methylpyridine?

Chemical properties

light yellow crystalline flakes

The Uses of 2-Amino-5-methylpyridine

Intermediate.

What are the applications of Application

2-Amino-5-methylpyridine is a pharmaceutical intermediate compound used in the preparation of Abametapir, a prescription drug used to treat head lice infestations in people 6 months of age and older.

Safety Profile

Poison by ingestion,subcutaneous, and skin contact routes. When heated todecomposition it emits toxic vapors of NOx.

Purification Methods

Crystallise it from acetone. [Beilstein 22/9 V 289.]

Properties of 2-Amino-5-methylpyridine

Melting point:	76-77 °C(lit.)
Boiling point:	227 °C(lit.)
Density	227
vapor pressure	3.706Pa at 25℃
refractive index	1,524-1,528
Flash point:	118°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	1000g/l
form	Crystalline Powder, Crystals or Flakes
pka	pK1: 7.22(+1) (25°C)
color	White to light yellow
Sensitive	Hygroscopic
BRN	107050
CAS DataBase Reference	1603-41-4(CAS DataBase Reference)
NIST Chemistry Reference	2-Pyridinamine, 5-methyl-(1603-41-4)
EPA Substance Registry System	6-Amino-3-picoline (1603-41-4)

Safety information for 2-Amino-5-methylpyridine

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.