2-Amino-5-methylpyridine
Synonym(s):2-Amino-5-picoline;6-Amino-3-picoline
- CAS NO.：1603-41-4
- Empirical Formula: C6H8N2
- Molecular Weight: 108.14
- MDL number: MFCD00006328
- EINECS: 216-503-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 13:37:16
What is 2-Amino-5-methylpyridine?
Chemical properties
light yellow crystalline flakes
The Uses of 2-Amino-5-methylpyridine
Intermediate.
What are the applications of Application
2-Amino-5-methylpyridine is a pharmaceutical intermediate compound used in the preparation of Abametapir, a prescription drug used to treat head lice infestations in people 6 months of age and older.
Safety Profile
Poison by ingestion,subcutaneous, and skin contact routes. When heated todecomposition it emits toxic vapors of NOx.
Purification Methods
Crystallise it from acetone. [Beilstein 22/9 V 289.]
Properties of 2-Amino-5-methylpyridine
| Melting point: | 76-77 °C(lit.) |
| Boiling point: | 227 °C(lit.) |
| Density | 227 |
| vapor pressure | 3.706Pa at 25℃ |
| refractive index | 1,524-1,528 |
| Flash point: | 118°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 1000g/l |
| form | Crystalline Powder, Crystals or Flakes |
| pka | pK1: 7.22(+1) (25°C) |
| color | White to light yellow |
| Sensitive | Hygroscopic |
| BRN | 107050 |
| CAS DataBase Reference | 1603-41-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinamine, 5-methyl-(1603-41-4) |
| EPA Substance Registry System | 6-Amino-3-picoline (1603-41-4) |
Safety information for 2-Amino-5-methylpyridine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-5-methylpyridine
| InChIKey | CMBSSVKZOPZBKW-UHFFFAOYSA-N |
2-Amino-5-methylpyridine manufacturer
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