2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride
- CAS NO.：56824-22-7
- Empirical Formula: C7H15Cl2N
- Molecular Weight: 184.1
- MDL number: MFCD00012717
- EINECS: 260-395-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:56:26
What is 2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride?
The Uses of 2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride
2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride is an intermediate used in the synthesis of reversed lactam analogues of ARC-111 with potent topoisomerase I-targeting activity and cytotoxcity.
The Uses of 2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride
2-(2-Chloroethyl)-1-methylpyrrolidine hydrochloride was used in the synthesis of N-[2-(1-methylpyrrolidin-2-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl) amide. It was used as reagent during the synthesis of 1-methyl-2-[2-[2-(2-phenylethyl)phenoxy]ethyl]pyrrolidine hydrochlochloride.
Properties of 2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride
| Melting point: | 98-102 °C(lit.) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Pale Beige to Beige |
| BRN | 6148386 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 56824-22-7(CAS DataBase Reference) |
Safety information for 2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(2-Chloroethyl)-N-methyl-pyrrolidine hydrochloride
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