2-(2-Chloroethoxy)ethanol
Synonym(s):Diethylene glycol monochlorohydrin
- CAS NO.:628-89-7
- Empirical Formula: C4H9ClO2
- Molecular Weight: 124.57
- MDL number: MFCD00002870
- EINECS: 211-059-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02

What is 2-(2-Chloroethoxy)ethanol?
Chemical properties
colourless liquid
The Uses of 2-(2-Chloroethoxy)ethanol
2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).
The Uses of 2-(2-Chloroethoxy)ethanol
2-(2-Chloroethoxy)ethanol is employed in the preparation of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine and 2-(2-azidoethoxy)ethanol.
The Uses of 2-(2-Chloroethoxy)ethanol
2-(2-Chloroethoxy)ethanol was used in the synthesis of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine (an antipsychotic drug) and 2-(2-azidoethoxy)ethanol.
Flammability and Explosibility
Non flammable
Properties of 2-(2-Chloroethoxy)ethanol
Boiling point: | 79-81 °C5 mm Hg(lit.) |
Density | 1.18 g/mL at 25 °C(lit.) |
vapor pressure | 22.66Pa at 20℃ |
refractive index | n |
Flash point: | 195 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | SOLUBLE |
form | Liquid |
pka | 14.34±0.10(Predicted) |
color | Clear |
Water Solubility | SOLUBLE |
BRN | 506015 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 628-89-7(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanol, 2-(2-chloroethoxy)-(628-89-7) |
EPA Substance Registry System | Ethanol, 2-(2-chloroethoxy)- (628-89-7) |
Safety information for 2-(2-Chloroethoxy)ethanol
Signal word | Danger |
Pictogram(s) |
![]() Corrosion Corrosives GHS05 ![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(2-Chloroethoxy)ethanol
InChIKey | LECMBPWEOVZHKN-UHFFFAOYSA-N |
2-(2-Chloroethoxy)ethanol manufacturer
JSK Chemicals
2Y
Phone:+91-9879767970
Whatsapp: +91-9879767970
product: 628-89-7 2-(2-Chloroethoxy)ethanol, 98% 99%
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