(1S,2S,3R,5S)-(+)-2,3-Pinanediol

Synonym(s):(+)-2-Hydroxyisopinocampheol;(1S,2S,3R,5S)-2,3-Pinanediol;(1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol;[1S-(1α,2α,3α,5α)]-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol

CAS NO.：18680-27-8
Empirical Formula: C10H18O2
Molecular Weight: 170.25
MDL number: MFCD00077851
EINECS: 606-096-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-05 11:59:05

(1S,2S,3R,5S)-(+)-2,3-Pinanediol Structural

What is (1S,2S,3R,5S)-(+)-2,3-Pinanediol?

Chemical properties

white to light beige crystalline powder, crystals

The Uses of (1S,2S,3R,5S)-(+)-2,3-Pinanediol

(1S,2S,3R,5S)-(+)-2,3-Pinanediol is a bicyclic monoterpene diols that has been shown to induce differentiation of S91 melanoma and PC12 pheochromocytoma cells and thus provide possible therapeutic and sunless tanning use. It is also used in the transformation of isopinocampheol and caryophyllene oxide.

The Uses of (1S,2S,3R,5S)-(+)-2,3-Pinanediol

(1S,2S,3R,5S)-(+)-Pinanediol can be used as a chiral reagent in the synthesis of homochiral α-hydroxyketones and in the resolution of prolineboronate esters.

Properties of (1S,2S,3R,5S)-(+)-2,3-Pinanediol

Melting point:	57-59 °C(lit.)
Boiling point:	239.9°C (rough estimate)
alpha	8.5 º (c=6.5, toluene)
Density	0.9409 (rough estimate)
refractive index	1.4494 (estimate)
Flash point:	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform, Methanol (Slightly), Toluene (Slightly)
form	Crystalline Powder, Crystals or Mass
pka	14.68±0.60(Predicted)
color	White to light beige
optical activity	[α]20/D +8.5°, c = 6.5 in toluene
BRN	1853591
CAS DataBase Reference	18680-27-8(CAS DataBase Reference)
NIST Chemistry Reference	(1S,2s,3r,5s)-(+)-pinanediol(18680-27-8)

Safety information for (1S,2S,3R,5S)-(+)-2,3-Pinanediol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.