(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine

Synonym(s):(1S,2S)-(−)-1,2-Diamino-1,2-diphenylethane

CAS NO.：29841-69-8
Empirical Formula: C14H16N2
Molecular Weight: 212.29
MDL number: MFCD00082751
EINECS: 608-420-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-06 16:20:44

(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine Structural

What is (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine?

Chemical properties

white to light yellow crystal powder

The Uses of (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine

(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine solvation agent, For synthesis of enantiopure ethylenediamines by chirality transfer (condensation with diketones followed by reductive cleavage), Co-catalyst in the Ru catalyzed enantioselective hydrogenation of aromatic ketones, Versatile ligand for the formation of metal complexes.1 Used in the synthesis of chiral tropocoronands which have potential utility in asymmetric catalysis

General Description

1,2-Diphenylethylenediamine is a chiral molecule, generally used as a chiral resolving agent and as a precursor of the chiral auxiliary. It is also used as a chiral solvating agent in NMR study.

Properties of (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine

Melting point:	83-85 °C(lit.)
Boiling point:	342.14°C (rough estimate)
alpha	-104 º (c=1.1, MeOH 25 ºC)
Density	1.0799 (rough estimate)
refractive index	-103 ° (C=1, EtOH)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka	9.78±0.10(Predicted)
form	crystal
color	white to pale yellow
optical activity	[α]20/D 102°, c = 1 in ethanol
Water Solubility	Insoluble in water.
Sensitive	Air Sensitive
BRN	3201645
CAS DataBase Reference	29841-69-8(CAS DataBase Reference)

Safety information for (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.