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HomeProduct name list(1R,2S)-1-Amino-2-indanol

(1R,2S)-1-Amino-2-indanol

Synonym(s):(1R,2S)-(+)-cis-1-Amino-2-hydroxyindane

  • CAS NO.:136030-00-7
  • Empirical Formula: C9H11NO
  • Molecular Weight: 149.19
  • MDL number: MFCD00216656
  • EINECS: 603-940-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-16 14:59:45
(1R,2S)-1-Amino-2-indanol  Structural

What is (1R,2S)-1-Amino-2-indanol ?

Chemical properties

(1R,2S)-1-Amino-2-indanol is white to light yellow crystal powder

The Uses of (1R,2S)-1-Amino-2-indanol

This cis-aminoindanol and its antipode have been used in the preparation of a series of potent HIV-1 protease inhibitory peptides. Also, they have served as chiral ligands in the catalytic asymmetric reduction of prochiral ketones with boranes.

What are the applications of Application

(1R,2S)-(+)-cis-1-Amino-2-indanol is a compound used in the preparation of HIV-1 protease inhibitory peptides

Properties of (1R,2S)-1-Amino-2-indanol

Melting point: 118-121 °C(lit.)
Boiling point: 270.27°C (rough estimate)
alpha  44.5 º (c=1, methanol)
Density  1.0753 (rough estimate)
refractive index  43 ° (C=1, MeOH)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  soluble in Methanol
form  Powder
pka 14.79±0.40(Predicted)
color  White to light beige
optical activity [α]22/D +63°, c = 0.2 in chloroform
Water Solubility  soluble
BRN  2803743
CAS DataBase Reference 136030-00-7(CAS DataBase Reference)

Safety information for (1R,2S)-1-Amino-2-indanol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (1R,2S)-1-Amino-2-indanol

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