(1R,2S)-1-Amino-2-indanol

Synonym(s):(1R,2S)-(+)-cis-1-Amino-2-hydroxyindane

CAS NO.：136030-00-7
Empirical Formula: C9H11NO
Molecular Weight: 149.19
MDL number: MFCD00216656
EINECS: 603-940-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-16 14:59:45

What is (1R,2S)-1-Amino-2-indanol ?

Chemical properties

(1R,2S)-1-Amino-2-indanol is white to light yellow crystal powder

The Uses of (1R,2S)-1-Amino-2-indanol

This cis-aminoindanol and its antipode have been used in the preparation of a series of potent HIV-1 protease inhibitory peptides. Also, they have served as chiral ligands in the catalytic asymmetric reduction of prochiral ketones with boranes.

What are the applications of Application

(1R,2S)-(+)-cis-1-Amino-2-indanol is a compound used in the preparation of HIV-1 protease inhibitory peptides

Properties of (1R,2S)-1-Amino-2-indanol

Melting point:	118-121 °C(lit.)
Boiling point:	270.27°C (rough estimate)
alpha	44.5 º (c=1, methanol)
Density	1.0753 (rough estimate)
refractive index	43 ° (C=1, MeOH)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Methanol
form	Powder
pka	14.79±0.40(Predicted)
color	White to light beige
optical activity	[α]22/D +63°, c = 0.2 in chloroform
Water Solubility	soluble
BRN	2803743
CAS DataBase Reference	136030-00-7(CAS DataBase Reference)

Safety information for (1R,2S)-1-Amino-2-indanol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.