15-HYDROXYPENTADECANOIC ACID

CAS NO.：4617-33-8
Empirical Formula: C15H30O3
Molecular Weight: 258.4
MDL number: MFCD00039535
EINECS: 225-026-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 15-HYDROXYPENTADECANOIC ACID?

Description

15-hydroxy Pentadecanoic acid is a hydroxylated fatty acid that has been used in the synthesis of the macrocyclic lactone musk compounds exaltolide and phoracantholide I. [Matreya, LLC. Catalog No. 1881]

Chemical properties

white to light yellow crystalline powder

The Uses of 15-HYDROXYPENTADECANOIC ACID

15-Hydroxypentadecanoic acid is suitable reagent used in the following studies:

As an internal standard in the quantification of formation of 11-hydroxylauric acid by gas chromatography.
In the synthesis of [16-¹⁴C]16DCA (DCA= dicarboxylic acid) by one-carbon elongation procedure at C15.
As an internal standard for the normalization of intensities in the mass spectra of plant cutin polymer.

It may be used in the synthesis of 5-pentadecanolide on dealuminated HY zeolite and also fatty acid analog of podophyllotoxin.

Definition

ChEBI: An omega-hydroxy fatty acid that is pentadecanoic acid in which one of the hydrogens of the terminal methyl group has been replaced by a hydroxy group.

General Description

15-Hydroxypentadecanoic acid undergoes lactonization reaction catalyzed by Mucor javanicus L46 and Mucor miehei to afford macrocyclic mono- and oligolactone derivatives. Its lipase-catalyzed synthesis from 15-tetracosenoic acid in Malania Olcifera Chum oil has been proposed. It also participates in the biosynthesis of pentadecanolide.

Properties of 15-HYDROXYPENTADECANOIC ACID

Melting point:	85-89 °C(lit.)
Boiling point:	174-220 °C(Press: 4 Torr)
Density	0.963±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly, Sonicated), DMSO (Slightly)
form	Solid
pka	4.78±0.10(Predicted)
color	White to Off-White
BRN	1240100
CAS DataBase Reference	4617-33-8(CAS DataBase Reference)

Safety information for 15-HYDROXYPENTADECANOIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.