BETULINIC ACID METHYL ESTER
- CAS NO.：2259-06-5
- Empirical Formula: C31H50O3
- Molecular Weight: 470.73
- MDL number: MFCD00017379
- EINECS: 218-857-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-04 20:04:50
What is BETULINIC ACID METHYL ESTER?
Description
Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC50 = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).
What are the applications of Application
Methyl betulinate is a pentacyclic lupane terpene
Definition
ChEBI: Betulinic acid methyl ester is a triterpenoid.
Properties of BETULINIC ACID METHYL ESTER
| Melting point: | 222-223°C |
| Boiling point: | 523.5±33.0 °C(Predicted) |
| Density | 1.036±0.06 g/cm3(Predicted) |
| pka | 15.16±0.70(Predicted) |
| form | A solid |
Safety information for BETULINIC ACID METHYL ESTER
Computed Descriptors for BETULINIC ACID METHYL ESTER
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