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HomeProduct name list(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE

(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE

(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Structural

What is (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE?

The Uses of (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE

(1,3-Dioxolan-2-ylmethyl)magnesium bromide is a Grignard reagent that can be used to prepare:

  • 3-[11C]-Propionaldehyde, a key intermediate for the synthesis of radiolabeled compound [11C]SN-38, wherein SN-38 is 7-ethyl-10-hydroxy camptothecin.
  • 1-[(S)-2,2-Dimethyl-(1,3)-dioxolan-4-yl]-4-(1,3-dioxolan2-yl)-2-ol by reacting with D-glyceraldehyde, which is further used to synthesize unsaturated nucleosides.
  • A bicyclo carboxylate intermediate, which is employed in the total synthesis of spirovibsanin A.

Properties of (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE

Boiling point: 65-67 °C
Density  0.938 g/mL at 25 °C
Flash point: −4 °F
form  Powder
color  White to off-white to pale brown

Safety information for (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H302:Acute toxicity,oral
H314:Skin corrosion/irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H351:Carcinogenicity
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378:In case of fire: Use … for extinction.
P403+P235:Store in a well-ventilated place. Keep cool.

Computed Descriptors for (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE

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