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HomeProduct name list1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Structural

What is 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)?

Description

DSPG, also known as 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, is a phospholipid molecule with phosphate polar head connected to two non-polar lipid (stearic acid) by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles.

The Uses of 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin.

Properties of 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

storage temp.  -20°C
solubility  Chloroform:Methanol:Water = 2:1:0.1 (Very Slightly)
form  Solid
color  White to Off-White
Stability: Hygroscopic

Safety information for 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

Computed Descriptors for 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

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