11-KETO FLUPROSTENOL
- CAS NO.：62145-07-7
- Empirical Formula: C23H27F3O6
- Molecular Weight: 456.45
- MDL number: MFCD05863541
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:09
What is 11-KETO FLUPROSTENOL?
Description
11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor.1 Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.2
What are the applications of Application
11-keto Fluprostenol is An analog of prostaglandin D2
Definition
ChEBI: 11-keto Fluprostenol is a prostanoid.
References
1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α Nature 250(464),330-331(1974).
2. Monneret, G., Cossette, C., Gravel, S., et al. 15R-
Properties of 11-KETO FLUPROSTENOL
| Boiling point: | 627.3±55.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| solubility | PBS (7.2): 29 mg/ml |
| pka | 4.76±0.10(Predicted) |
Safety information for 11-KETO FLUPROSTENOL
Computed Descriptors for 11-KETO FLUPROSTENOL
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