Fluprostenol

Synonym(s):(±)-16-(3-Trifluoromethylphenoxy)tetranorprostaglandin F_2α

CAS NO.：40666-16-8
Empirical Formula: C23H29F3O6
Molecular Weight: 458.47
MDL number: MFCD03427566
EINECS: 255-029-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-07-14 17:48:06

What is Fluprostenol?

The Uses of Fluprostenol

Fluprostenol is a prostaglandin F (FP) receptor agonist.

What are the applications of Application

Fluprostenol is a prostaglandin F (FP) receptor agonist

Definition

ChEBI: Fluprostenol is an organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea. It has a role as an antiglaucoma drug, an antihypertensive agent, a prostaglandin receptor agonist, a female contraceptive drug and an abortifacient. It is a prostaglandins Falpha, a hydroxy monocarboxylic acid and a member of (trifluoromethyl)benzenes.

Properties of Fluprostenol

Boiling point:	608.0±55.0 °C(Predicted)
Density	1.335
storage temp.	−20°C
form	Colorless oil dissolved in ethanol (1mg/100μl).
pka	4.76±0.10(Predicted)

Safety information for Fluprostenol

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.