1-Piperidinepropanol

Synonym(s):1-(3-Hydroxypropyl)piperidine

CAS NO.：104-58-5
Empirical Formula: C8H17NO
Molecular Weight: 143.23
MDL number: MFCD00023781
EINECS: 203-216-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:42:50

What is 1-Piperidinepropanol?

The Uses of 1-Piperidinepropanol

1-Piperidinepropanol is used in preparation of Ionizable Amine lipids for lipid Nanoparticle compounds that deliver Nucleic Acids.

The Uses of 1-Piperidinepropanol

Reactant in: Mitsunobu reaction of intramolecular nitrile oxide-alkene cycloadditions1 Suzuki-coupling2Reactant for synthesis of: Histamine H3 receptor antagonists3 Protein lysine methyltransferase G9a inhibitors4 Serotonin-4 receptors antagonists5 Checkpoint kinase Chk2 inhibitors6

What are the applications of Application

1-Piperidinepropanol is used to prepare isothiourea and was a reactant in Mitsunobu reaction of intramolecular nitrile oxide-alkene cycloadditions

Properties of 1-Piperidinepropanol

Boiling point:	94-95 °C/0.5 mmHg (lit.)
Density	0.944 g/mL at 25 °C (lit.)
refractive index	n20/D 1.4775(lit.)
Flash point:	208 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	liquid
pka	15.12±0.10(Predicted)
color	Colourless to light yellow
CAS DataBase Reference	104-58-5(CAS DataBase Reference)
NIST Chemistry Reference	1-Piperidinepropanol(104-58-5)

Safety information for 1-Piperidinepropanol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.