1-Ethylpiperazine
Synonym(s):1-Ethylpiperazine
- CAS NO.：5308-25-8
- Empirical Formula: C6H14N2
- Molecular Weight: 114.19
- MDL number: MFCD00059912
- EINECS: 226-166-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is 1-Ethylpiperazine?
Chemical properties
clear colorless to yellow liquid
The Uses of 1-Ethylpiperazine
1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.
The Uses of 1-Ethylpiperazine
1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.
Synthesis Reference(s)
The Journal of Organic Chemistry, 22, p. 713, 1957 DOI: 10.1021/jo01357a621
Flammability and Explosibility
Flammable
Properties of 1-Ethylpiperazine
| Melting point: | -60 °C |
| Boiling point: | 157 °C(lit.) |
| Density | 0.899 g/mL at 25 °C(lit.) |
| vapor pressure | 2.48hPa at 20℃ |
| refractive index | n |
| Flash point: | 110 °F |
| storage temp. | 2-8°C |
| solubility | soluble |
| form | Liquid |
| pka | 9.27±0.10(Predicted) |
| Specific Gravity | 0.899 |
| color | Clear colorless to yellow |
| Water Solubility | soluble |
| Sensitive | Air Sensitive |
| BRN | 102971 |
| CAS DataBase Reference | 5308-25-8(CAS DataBase Reference) |
| NIST Chemistry Reference | N-ethylpiperazine(5308-25-8) |
| EPA Substance Registry System | Piperazine, 1-ethyl- (5308-25-8) |
Safety information for 1-Ethylpiperazine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation H317:Sensitisation, Skin H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Ethylpiperazine
| InChIKey | WGCYRFWNGRMRJA-UHFFFAOYSA-N |
1-Ethylpiperazine manufacturer
Kubo Combustion Efficiency Chemicals Pvt Ltd
1Y
Phone:+91-2235912360
product: N-Ethyl piperazine 98%
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