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HomeProduct name list1-Ethylpiperazine

1-Ethylpiperazine

Synonym(s):1-Ethylpiperazine

  • CAS NO.:5308-25-8
  • Empirical Formula: C6H14N2
  • Molecular Weight: 114.19
  • MDL number: MFCD00059912
  • EINECS: 226-166-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
1-Ethylpiperazine Structural

What is 1-Ethylpiperazine?

Chemical properties

clear colorless to yellow liquid

The Uses of 1-Ethylpiperazine

1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.

The Uses of 1-Ethylpiperazine

1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.

Synthesis Reference(s)

The Journal of Organic Chemistry, 22, p. 713, 1957 DOI: 10.1021/jo01357a621

Flammability and Explosibility

Flammable

Properties of 1-Ethylpiperazine

Melting point: -60 °C
Boiling point: 157 °C(lit.)
Density  0.899 g/mL at 25 °C(lit.)
vapor pressure  2.48hPa at 20℃
refractive index  n20/D 1.469(lit.)
Flash point: 110 °F
storage temp.  2-8°C
solubility  soluble
form  Liquid
pka 9.27±0.10(Predicted)
Specific Gravity 0.899
color  Clear colorless to yellow
Water Solubility  soluble
Sensitive  Air Sensitive
BRN  102971
CAS DataBase Reference 5308-25-8(CAS DataBase Reference)
NIST Chemistry Reference N-ethylpiperazine(5308-25-8)
EPA Substance Registry System Piperazine, 1-ethyl- (5308-25-8)

Safety information for 1-Ethylpiperazine

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H314:Skin corrosion/irritation
H317:Sensitisation, Skin
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-Ethylpiperazine

InChIKey WGCYRFWNGRMRJA-UHFFFAOYSA-N

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