1-Bromo-2-(1-methylethyl)benzene

CAS NO.：7073-94-1
Empirical Formula: C9H11Br
Molecular Weight: 199.09
MDL number: MFCD00051567
EINECS: 230-370-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-01-08 16:30:38

What is 1-Bromo-2-(1-methylethyl)benzene?

Synthesis

1-Bromo-2-(1-methylethyl)benzene is synthesised using 1-bromo-2-isopropenylbenzene as a raw material by chemical reaction. The specific synthesis steps are as follows:
General procedure: The mixture of S-3 (1 equivalent), TsNHNH2 (5 equivalent), NaOAc·3H2O (5equivalent), and THF (0.3 M) were heated at reflux for 24 h. When the reaction wascomplete as determined by TLC, cooling to room temperature and adding H2O. Thecrude mixture was extracted with EtOAc (3x20 mL) and the combined organicextracts were washed with brine, dried over anhydrous Na2SO4, and concentrated invacuo. The crude was then purified by column chromatography (Petroleum ether) onsilicagel to give 1-Bromo-2-(1-methylethyl)benzene as a colorless oil.

Properties of 1-Bromo-2-(1-methylethyl)benzene

Melting point:	-58.8°C
Boiling point:	90 °C
Density	1.30
refractive index	1.5410
Flash point:	90-92°C/15mm
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
Specific Gravity	1.30
color	Colorless to Light orange to Yellow
Water Solubility	Insoluble in water.
BRN	1857014
InChI	InChI=1S/C9H11Br/c1-7(2)8-5-3-4-6-9(8)10/h3-7H,1-2H3
CAS DataBase Reference	7073-94-1(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-bromo-2-(1-methylethyl)-(7073-94-1)

Safety information for 1-Bromo-2-(1-methylethyl)benzene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H401:Hazardous to the aquatic environment, acute hazard H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…