1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Synonym(s):1-(5-Isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide
- CAS NO.:84477-87-2
- Empirical Formula: C14H17N3O2S
- Molecular Weight: 291.37
- MDL number: MFCD00063403
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE?
What are the applications of Application
H-7 is An inhibitor of PKA and PKC
Definition
ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Biological Activity
Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.
Properties of 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Boiling point: | 495.3±55.0 °C(Predicted) |
Density | 1.277±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | ethanol: 20 mg/mL |
form | Solid |
pka | 7.69±0.40(Predicted) |
color | White to light yellow |
BRN | 5482740 |
Safety information for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Computed Descriptors for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1,1’-CARBONYLDIIMIDAZOLE DIETHYL AMINOMALONATE HYDROCHLORIDE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
(R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE
(S)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
1-BENZENESULFONYL-PIPERAZINE
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
1-METHANESULFONYL-PIPERAZINE
1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE
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