1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Synonym(s):1-(5-Isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide
- CAS NO.:84477-87-2
- Empirical Formula: C14H17N3O2S
- Molecular Weight: 291.37
- MDL number: MFCD00063403
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE?
What are the applications of Application
H-7 is An inhibitor of PKA and PKC
Definition
ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Biological Activity
Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.
Properties of 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Boiling point: | 495.3±55.0 °C(Predicted) |
Density | 1.277±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | ethanol: 20 mg/mL |
form | Solid |
pka | 7.69±0.40(Predicted) |
color | White to light yellow |
BRN | 5482740 |
Safety information for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Computed Descriptors for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
(R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE
(S)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
1-BENZENESULFONYL-PIPERAZINE
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
1-METHANESULFONYL-PIPERAZINE
1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE
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