1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Synonym(s):1-(5-Isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide
- CAS NO.：84477-87-2
- Empirical Formula: C14H17N3O2S
- Molecular Weight: 291.37
- MDL number: MFCD00063403
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE?
What are the applications of Application
H-7 is An inhibitor of PKA and PKC
Definition
ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Biological Activity
Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.
Properties of 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
| Boiling point: | 495.3±55.0 °C(Predicted) |
| Density | 1.277±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ethanol: 20 mg/mL |
| form | Solid |
| pka | 7.69±0.40(Predicted) |
| color | White to light yellow |
| BRN | 5482740 |
Safety information for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Computed Descriptors for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
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