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HomeProduct name list1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

Synonym(s):1-(5-Isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Structural

What is 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE?

What are the applications of Application

H-7 is An inhibitor of PKA and PKC

Definition

ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Biological Activity

Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.

Properties of 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

Boiling point: 495.3±55.0 °C(Predicted)
Density  1.277±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  ethanol: 20 mg/mL
form  Solid
pka 7.69±0.40(Predicted)
color  White to light yellow
BRN  5482740

Safety information for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

Computed Descriptors for 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

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