1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
- CAS NO.:84468-24-6
- Empirical Formula: C13H15N3O2S
- Molecular Weight: 277.34
- MDL number: MFCD00209852
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE?
Chemical properties
Pale Yellow Crystalline Solid
The Uses of 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Exhibited potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases
Definition
ChEBI: 5-(1-piperazinylsulfonyl)isoquinoline is a member of isoquinolines.
Biological Activity
Inhibitor of protein kinase C. Vasodilator.
Properties of 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Melting point: | >240°C (dec.) |
Boiling point: | 497.4±55.0 °C(Predicted) |
Density | 1.332±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | DMSO, Methanol, Water |
form | Off-white lyophilized solid. |
pka | 7.66±0.10(Predicted) |
color | Off-White to Pale Yellow |
CAS DataBase Reference | 84468-24-6(CAS DataBase Reference) |
Safety information for 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Related products of tetrahydrofuran
Piperazine
Histamine dihydrochloride
1-(8-CHLORO-5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
H-7 DIHYDROCHLORIDE
(S)-5-(3-Benzyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride
(S) 5-(3-Isopropyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride
(R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
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