β-Tocopherol

CAS NO.：148-03-8
Empirical Formula: C28H48O2
Molecular Weight: 416.68
MDL number: MFCD00036171
EINECS: 205-708-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 15:53:33

What is β-Tocopherol?

Description

(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an EC₅₀ value of 68.2 μM. (±)-β-Tocopherol (100 μM) inhibits LPS-induced COX-2 gene expression in mouse RAW 264.7 macrophage cells. Unlike (±)-α-tocopherol , (±)-β-tocopherol does not inhibit smooth muscle cell proliferation, decrease PKC activity, increase phosphoprotein phosphatase 2A (PP2A) activity, or modify expression of the α-tropomyosin gene. [Matreya, LLC. Catalog No. 1071]

The Uses of β-Tocopherol

One of the naturally occurring forms of Vitamin E. Is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.

What are the applications of Application

rac-β-Tocopherol solution is a naturally occurring form of Vitamin E

Definition

ChEBI: Beta-tocopherol is a tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts. It has a role as a plant metabolite and a food component. It is a vitamin E and a tocopherol.

Properties of β-Tocopherol

Melting point:	<25℃
Boiling point:	474.94°C (rough estimate)
Density	0.9882 (rough estimate)
refractive index	1.4480 (estimate)
Flash point:	-23 °C
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Ethanol (Slightly), Ethyl Acetate (Slightly), Methanol (
pka	11.05±0.40(Predicted)
form	Oil
color	Colourless to Yellow
EPA Substance Registry System	2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel- (148-03-8)

Safety information for β-Tocopherol

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H225:Flammable liquids H304:Aspiration hazard H315:Skin corrosion/irritation H336:Specific target organ toxicity,single exposure; Narcotic effects H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool.