(+/-)-NICOTINE
- CAS NO.:22083-74-5
- Empirical Formula: C10H14N2
- Molecular Weight: 162.23
- MDL number: MFCD00065370
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:03

What is (+/-)-NICOTINE?
Chemical properties
(+/-)-NICOTINE is Colourless Liquid
The Uses of (+/-)-NICOTINE
(+/-)-NICOTINE is an alkaloid isolated from plants. It is an active stimulant, having both addictive and carcinogenic properties.
The Uses of (+/-)-NICOTINE
This is the unnatural isomer of Nicotine
The Uses of (+/-)-NICOTINE
Nicotine is an alkaloid isolated from plants. Nicotine is an active stimulant, having both addictive and carcinogenic properties. Nicotine can be absorbed through the alimentary canal, respiratory tra ct and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic.
What are the applications of Application
(±)-Nicotine is an alkaloid found in tobacco with addictive and teratogenic properties
Definition
ChEBI: 3-(1-methylpyrrolidin-2-yl)pyridine is an N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2. It is a N-alkylpyrrolidine, a pyridine alkaloid and a pyrrolidine alkaloid.
Biochem/physiol Actions
Prototype nicotinic acetylcholine receptor agonist.
Purification Methods
(+/-)-NICOTINE is purified by fractional distillation. Its solubility in EtOH is ~5%. The picrate forms yellow needles from hot H2O and has m 219o. The methiodide has m 219o (from MeOH). [Craig J Am Chem Soc 55 2854 1933, Nakane & Hutchinson J Org Chem 43 3922 1978, Beilstein 23/6 V 64.] POISONOUS.
Properties of (+/-)-NICOTINE
Melting point: | -79 °C |
Boiling point: | 67°C/0.5 mm |
Density | 1.02 g/mL at 25 °C(lit.) |
Flash point: | 101 °C |
storage temp. | Refrigerator |
solubility | ethanol: 50 mg/mL |
form | liquid |
pka | 8.02(at 25℃) |
color | yellow |
optical activity | [α]25/D 0°(lit.) |
BRN | 82108 |
Stability: | Air Sensitive |
CAS DataBase Reference | 22083-74-5(CAS DataBase Reference) |
Safety information for (+/-)-NICOTINE
Signal word | Danger |
Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Environment GHS09 |
GHS Hazard Statements |
H301:Acute toxicity,oral H310:Acute toxicity,dermal H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for (+/-)-NICOTINE
New Products
Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2,2-Difluoropropylamine hydrochloride tert-butyl 3-bromoazetidine-1-carboxylate (R)-1-Boc-3-hydroxypyrrolidine DIFLUOROACETIC ANHYDRIDE 2,2-Difluoropropionic acid Diallylamine, 99% Calcium hydroxide, 95% Aluminum oxide, basic 2-Bromophenylacetonitrile, 97% L-tert-Leucine,97% N-Hydroxy-2-methylpropanimidamide 4-(3,4-Dichlorophenyl)-3,4-Dihydro-N-Methyl-1-(2H)-Naphthalenimine (Schiff Base) 2-AMINO-3,5-DIBROMO BENZALDEHYDE [ADBA] L-Glutamic Acid Dimethyl Ester Hcl 10-Methoxy-5H-dibenz[b,f]azepine 5-Cyanophthalide N, N-Carbonyldiimidazole (CDI) Dibenzoyl Peroxide Titanium Dioxide 2-(Methylthio) Benzonitrile Sodium Acetate Anhydrous Allopurinol 1,5-DibromopentaneRelated products of tetrahydrofuran






![NICOTINE, L-, [N-METHYL-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB4681795.gif)

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