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HomeProduct name list(+/-)-NICOTINE

(+/-)-NICOTINE

(+/-)-NICOTINE Structural

What is (+/-)-NICOTINE?

Chemical properties

(+/-)-NICOTINE is Colourless Liquid

The Uses of (+/-)-NICOTINE

(+/-)-NICOTINE is an alkaloid isolated from plants. It is an active stimulant, having both addictive and carcinogenic properties.

The Uses of (+/-)-NICOTINE

This is the unnatural isomer of Nicotine

The Uses of (+/-)-NICOTINE

Nicotine is an alkaloid isolated from plants. Nicotine is an active stimulant, having both addictive and carcinogenic properties. Nicotine can be absorbed through the alimentary canal, respiratory tra ct and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic.

What are the applications of Application

(±)-Nicotine is an alkaloid found in tobacco with addictive and teratogenic properties

Definition

ChEBI: 3-(1-methylpyrrolidin-2-yl)pyridine is an N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2. It is a N-alkylpyrrolidine, a pyridine alkaloid and a pyrrolidine alkaloid.

Biochem/physiol Actions

Prototype nicotinic acetylcholine receptor agonist.

Purification Methods

(+/-)-NICOTINE is purified by fractional distillation. Its solubility in EtOH is ~5%. The picrate forms yellow needles from hot H2O and has m 219o. The methiodide has m 219o (from MeOH). [Craig J Am Chem Soc 55 2854 1933, Nakane & Hutchinson J Org Chem 43 3922 1978, Beilstein 23/6 V 64.] POISONOUS.

Properties of (+/-)-NICOTINE

Melting point: -79 °C
Boiling point: 67°C/0.5 mm
Density  1.02 g/mL at 25 °C(lit.)
Flash point: 101 °C
storage temp.  Refrigerator
solubility  ethanol: 50 mg/mL
form  liquid
pka 8.02(at 25℃)
color  yellow
optical activity [α]25/D 0°(lit.)
BRN  82108
Stability: Air Sensitive
CAS DataBase Reference 22083-74-5(CAS DataBase Reference)

Safety information for (+/-)-NICOTINE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Environment
GHS09
GHS Hazard Statements H301:Acute toxicity,oral
H310:Acute toxicity,dermal
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P262:Do not get in eyes, on skin, or on clothing.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for (+/-)-NICOTINE

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