(+)-GALLOCATECHIN
- CAS NO.:970-73-0
- Empirical Formula: C15H14O7
- Molecular Weight: 306.27
- MDL number: MFCD06798946
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:09
What is (+)-GALLOCATECHIN?
Description
(+)-Gallocatechin is a polyphenol and flavonoid that has been isolated from the leaves of tea plants and has diverse biological activities. It inhibits the adherence of P. gingivalis onto human buccal epithelial cells by more than 50% when used at a concentration of 250 μg/ml. (+)-Gallocatechin has antimutagenic properties in UV-irradiated E. coli cells. It inhibits cell death induced by D-galactosamine and TNF-α in primary cultured mouse hepatocytes by 29.9% when used at a concentration of 80 μM. (+)-Gallocatechin (100 μM) inhibits HCT116 colorectal cancer cell proliferation by 57%.
The Uses of (+)-GALLOCATECHIN
(+)-Gallocatechin is antioxidant isomer of (-)-Gallocatechin (G188990), a potential cancer chemopreventive agent that inhibits the growth and adherence of P. gingivalis onto the buccal epithelial cells. An epimer of (-)-Epigallocatechin (E588940).
Definition
ChEBI: A gallocatechin that has (2R,3S)-configuration. It is found in green tea and bananas.
Properties of (+)-GALLOCATECHIN
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly, Sonicated), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
form | Solid |
pka | 9.02±0.15(Predicted) |
Boiling point: | 685.6±55.0 °C(Predicted) |
Density | 1.695±0.06 g/cm3(Predicted) |
Melting point: | 218 °C(Solv: water (7732-18-5)) |
color | White to Pale Brown |
Stability: | Hygroscopic |
Safety information for (+)-GALLOCATECHIN
Computed Descriptors for (+)-GALLOCATECHIN
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Rimegepant Impurity 3 Ivermectin EP Impurity B Fosfomycin EP impurity D Tubulysin F Tubulysin M (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin A Diethyl Aluminium Cyanide (1.0 M in Toluene) Imeglimin Hydrochloride IH Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-Ethoxy-4-nitrobenzoic acid Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester Methyl 4-amino-3-(pyrrolidin-1-yl)benzoate 2-Chloro-3-(chloromethyl)pyridine 3-Morpholino-5,6-dihydropyridin-2(1H)-one 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucito 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidineRelated products of tetrahydrofuran
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