ZINQUIN ETHYL ESTER
- CAS NO.:151606-29-0
- Empirical Formula: C19H18N2O5S
- Molecular Weight: 386.42
- MDL number: MFCD00797629
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is ZINQUIN ETHYL ESTER?
Chemical properties
White or Pale Blue Crystalline Solid
The Uses of ZINQUIN ETHYL ESTER
A fluorescent reagent and indicator of intracellular zinc ions. An analogue of widely used indicator, TS-Q. Zinquin ethyl ester is membrane permeable therefore useful to detect intracellular zinc ions. Zinquin ethyl ester forms a complex with a zin
The Uses of ZINQUIN ETHYL ESTER
Zinquin ethyl ester is a lipophilic, zinc-sensitive, cell-permeable fluorescnet probe.
What are the applications of Application
Zinquin, Free Acid is a Zn2+ specific fluorophore that forms zinquin-Zn2+ complexes
Biochem/physiol Actions
Zinquin is a membrane-permeant fluorophore. It is used to detect zinc in cells by UV fluorescence. Zinquin ethyl ester can be used to monitor the change in intracellular concentrations of Zn2+ in thymocytes and hepatocytes. The ester is excited at 368nm and emits at 490nm.
Properties of ZINQUIN ETHYL ESTER
Melting point: | 112-114°C |
Boiling point: | 608.0±65.0 °C(Predicted) |
Density | 1.412±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: soluble |
form | crystals |
pka | pK1 (quinoline nitrogen): <2; pK (carboxylic acid proton): 5.77 ±0.03; pK (sulfonamide proton): 9.91±0.02(at 25℃) |
color | off-white |
λmax | 368 nm |
Biological Applications | Zinc indicator; detecting apoptosis |
Safety information for ZINQUIN ETHYL ESTER
Computed Descriptors for ZINQUIN ETHYL ESTER
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Zinquin Ethyl Ester
QUIN 2-AM
MQAE
2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n
TSQ
Gelatin
ZINQUIN ETHYL ESTER
ETHYL 2-[2-(2-METHYL-1-PROPENYL)-6-QUINOLYLOXY-8-P-TOLUENESULFONAMIDO)ACETATE
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