QUIN 2-AM
- CAS NO.：83104-85-2
- Empirical Formula: C38H43N3O18
- Molecular Weight: 829.76
- MDL number: MFCD00010285
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:47
What is QUIN 2-AM?
Description
Quin-2 AM is a cell-permeant acetoxymethyl ester of the high affinity fluorescent calcium indicator quin-2 . As quin-2 AM enters cells, it is hydrolyzed by intracellular esterases to produce quin-2. Quin-2 binds calcium with a Kd value of 115 nM. It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation and emission maxima for quin-2 are 339 and 492 nm, respectively.
The Uses of QUIN 2-AM
Quin 2-AM is a cell permeable fluorescent probe for Ca2+ that gives a large shift in the UV absorption spectrum and a 20-fold increase in fluorescence upon Ca2+ binding.
The Uses of QUIN 2-AM
2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)
The Uses of QUIN 2-AM
Fluorescent probe for measurement of calcium in biological systems and for selected divalent cations.
What are the applications of Application
Quin 2-AM is a cell permeable fluorescent probe for Ca2+
Properties of QUIN 2-AM
| Density | 1.360 |
| Flash point: | 113 °C |
| storage temp. | −20°C |
| solubility | DMSO: soluble |
| form | A solid |
| λmax | 348 nm |
| Biological Applications | Calcium indicator |
Safety information for QUIN 2-AM
Computed Descriptors for QUIN 2-AM
New Products
Tubulysin H Tubulysin E Tubulysin C Tubulysin F Potassium HMDS (1.0 M in THF) 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 4,4-DIFLUOROPIPERIDINE CYCLOBUTYLAMINE HYDROCHLORIDE 1-(1,1-Difluoroethyl)-2-fluorobenzene Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2,2-Difluoropropanol Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
![N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[2-[2-[5-[6-[(acetyloxy)methoxy]-3-oxo-3H-xanthen-9-yl]-2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]ethoxy]phenyl]glycine (acetyloxy)methyl ester](https://img.chemicalbook.in/CAS/20180702/GIF/1345980-40-6.gif)
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