(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
- CAS NO.：2093243-16-2
- Empirical Formula: C17H13NO4
- Molecular Weight: 295.29
- Update Date: 2023-04-23 13:52:06
What is (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?
The Uses of (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis.
Properties of (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
| Melting point: | >215°C (dec.) |
| Boiling point: | 536.9±50.0 °C(Predicted) |
| Density | 1.357±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 4.50±1.00(Predicted) |
| color | Yellow to Dark Yellow |
Safety information for (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Computed Descriptors for (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
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