Sorafenib Impurity 6

CAS NO.：1285533-84-7
Empirical Formula: C21H17F3N4O3
Molecular Weight: 430.38
MDL number: MFCD29041974
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:51

What is Sorafenib Impurity 6?

The Uses of Sorafenib Impurity 6

N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.

Properties of Sorafenib Impurity 6

Melting point:	187.6 °C
Boiling point:	498.1±45.0 °C(Predicted)
Density	1.399±0.06 g/cm3(Predicted)
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	13.39±0.70(Predicted)
color	Off-White to Light Brown

Safety information for Sorafenib Impurity 6

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P362:Take off contaminated clothing and wash before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…