(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

CAS NO.：73275-76-0
Empirical Formula: C24H31F3O6
Molecular Weight: 472.49
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 23:16:16

What is (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester?

Description

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.¹ The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug.²

What are the applications of Application

(+)-Fluprostenol methyl ester is a luteolytic F-series prostaglandin analog

References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F_2α Nature 250(464),330-331(1974).
2. Sorbera, L.A., and Casta?er, J. Travoprost Drugs Future 25(1),41-45(2000).

Properties of (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Boiling point:	568.8±50.0 °C(Predicted)
Density	1.281±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml
pka	13.43±0.20(Predicted)

Safety information for (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Computed Descriptors for (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

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(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

What is (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester?

Description

What are the applications of Application

References

Properties of (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Safety information for (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Computed Descriptors for (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

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