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HomeProduct name listXANTHURENIC ACID

XANTHURENIC ACID

Synonym(s):4,8-Dihydroxyquinaldic acid;4,8-Dihydroxyquinoline-2-carboxylic acid

  • CAS NO.:59-00-7
  • Empirical Formula: C10H7NO4
  • Molecular Weight: 205.17
  • MDL number: MFCD00006754
  • EINECS: 200-410-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 11:41:24
XANTHURENIC ACID Structural

What is XANTHURENIC ACID?

Chemical properties

ochre powder

The Uses of XANTHURENIC ACID

Xanthurenic acid can be used as a substrate for the synthesis of:

  • Silica-gel functionalized xanthurenic acid (4, 8-dihydroxyquinoline-2-carboxylic acid) as an adsorbent for metal ions.
  • N, N′-bis-((8-hydroxy-7-quinolinyl)methyl)-1,10-diaza-18-crown-6 ethers as fluorescent sensors of magnesium in living cells via one-pot Mannich reaction.
  • Poly-xanthurenic acid (poly-Xa) for biosensing applications.

The Uses of XANTHURENIC ACID

Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.

The Uses of XANTHURENIC ACID

caspase activator, guanylyl cyclase stimulant

What are the applications of Application

Xanthurenic acid is a potent activator of group II mGluRs

Definition

ChEBI: A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by hydroxy groups at C-4 and C-8.

storage

Room temperature

Purification Methods

It is precipitated by the addition of 2N formic acid to its solution in hot 2M ammonia (charcoal). The solid is filtered off, dried in a vacuum at ~80o in the dark. UV (H2O) has nm ( M-1cm-1): 243 (30,000) and 342 (6,500). The methyl ester has m 262o (from MeOH). It forms Cu2+, Zn2+, Fe2+ and Fe3+ salts. [Beilstein 22 III/IV 2513.]

Properties of XANTHURENIC ACID

Melting point: 297-298 °C (dec.)(lit.)
Boiling point: 343.83°C (rough estimate)
Density  1.3849 (rough estimate)
refractive index  1.5600 (estimate)
storage temp.  Sealed in dry,2-8°C
solubility  DMSO (Slightly, Heated), Water (Slightly, Heated)
form  Powder
pka 1.20±0.30(Predicted)
color  Ochre
Merck  14,10068
BRN  185954
CAS DataBase Reference 59-00-7(CAS DataBase Reference)

Safety information for XANTHURENIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for XANTHURENIC ACID

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