Vinylmagnesium bromide

CAS NO.：1826-67-1
Empirical Formula: C2H3BrMg
Molecular Weight: 131.26
MDL number: MFCD00000042
EINECS: 217-375-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-29 18:07:07

What is Vinylmagnesium bromide?

Chemical properties

Clear light brown to brown solution

The Uses of Vinylmagnesium bromide

Vinylmagnesium bromide solution (1 M in THF) may be used in the synthesis of 2-vinylchroman-4-ones by the conjugate addition with chromones in the presence of a Lewis acid.
It may also be used in the following transformations:

(S)-3-(benzyloxy)-4-oxo-butanoic acid methyl ester to methyl (3S,4S)-4-hydroxy-3-(phenylmethoxy)hex-5-enoate.
(R)-1-Azido-5,6-epoxyhexane to (S)-1-(4-azidobutyl)-2-propen-1-ol.
2,3-O-Isopropylidene-D-ribose to 1-[(4R,5S)-5-((1S)-1-hydroxyallyl)-2,2-dimethyl[1,3]dioxolan-4-yl]ethane-1,2-diol.
(4S,5S)-2,2-Dimethyl-5-vinyl[1,3]dioxolane-4-carbaldehyde to (1R,4R,5S)- and (1S,4R,5S)-1-(2,2-dimethyl-5-vinyl[1,3]dioxolan-4-yl)prop-2-en-1-ol.
Ethyl levulinate to ?-methyl-?-vinylbutyrolactone.

What are the applications of Application

Vinylmagnesium bromide solution is a Grignard reagent

Properties of Vinylmagnesium bromide

Density	0.981 g/mL at 25 °C
Flash point:	1 °F
storage temp.	Refrigerator
solubility	vigorous reaction
form	Solution
color	Clear light brown to brown
Water Solubility	vigorous reaction
BRN	3535841
CAS DataBase Reference	1826-67-1(CAS DataBase Reference)
EPA Substance Registry System	Magnesium, bromoethenyl- (1826-67-1)

Safety information for Vinylmagnesium bromide

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H260:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases H302:Acute toxicity,oral H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P231+P232:Handle under inert gas. Protect from moisture. P370+P378:In case of fire: Use … for extinction. P402+P404:Store in a dry place. Store in a closed container. P403+P235:Store in a well-ventilated place. Keep cool.