URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT

Description

Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.

The Uses of URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT

A phosphorylated derivative of the nucleoside Uridine. It is further phosphorylated by nucleoside diphosphokinase to form the triphosphate analogue.

The Uses of URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT

Uridine 5''-Diphosphate Sodium Salt is a potentially useful P2Y receptor agonist. It can be used in biological study and use in chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.

What are the applications of Application

Uridine 5′-diphosphate sodium salt is a potentially useful P2Y receptor agonist

Biochem/physiol Actions

P2Y receptor agonist.

in vitro

Uridine-5'-diphosphate disodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.