URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
Synonym(s):UDP sodium salt;Uridine 5′-(trihydrogen pyrophosphate) sodium salt
- CAS NO.：21931-53-3
- Empirical Formula: C9H12N2Na2O12P2
- Molecular Weight: 448.12
- MDL number: MFCD00084679
- EINECS: 999-999-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT?
Description
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.
The Uses of URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
A phosphorylated derivative of the nucleoside Uridine. It is further phosphorylated by nucleoside diphosphokinase to form the triphosphate analogue.
The Uses of URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
Uridine 5''-Diphosphate Sodium Salt is a potentially useful P2Y receptor agonist. It can be used in biological study and use in chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.
What are the applications of Application
Uridine 5′-diphosphate sodium salt is a potentially useful P2Y receptor agonist
Biochem/physiol Actions
P2Y receptor agonist.
in vitro
Uridine-5'-diphosphate disodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.
Properties of URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
| storage temp. | -20°C |
| solubility | H2O: soluble100 mg/mL, clear, colorless to very faintly yellow |
| form | Powder |
| color | White |
| Water Solubility | Soluble in water to 100mM |
| Stability: | Hygroscopic |
Safety information for URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H371:Specific target organ toxicity, single exposure |
Computed Descriptors for URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
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