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HomeProduct name listTubastatin-A

Tubastatin-A

Tubastatin-A Structural

What is Tubastatin-A?

Definition

ChEBI: A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminoca bonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).

Properties of Tubastatin-A

Density  1.28±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  insoluble in EtOH; insoluble in H2O; ≥10.75 mg/mL in DMSO
form  solid
pka 8.95±0.10(Predicted)
color  Off-white to light yellow

Safety information for Tubastatin-A

Computed Descriptors for Tubastatin-A

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