Tropisetron hydrochloride
Synonym(s):1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride;3-Tropanylindole-3-carboxylate monohydrochloride;ICS-205,930;Navoban;Tropisetron monohydrochloride
- CAS NO.：105826-92-4
- Empirical Formula: C17H21ClN2O2
- Molecular Weight: 320.81
- MDL number: MFCD02313825
- EINECS: 630-417-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Tropisetron hydrochloride?
Chemical properties
White to Off-White Crystalline Solid
The Uses of Tropisetron hydrochloride
Specific serotonin (5-HT3) receptor antagonist. Antiemetic.
The Uses of Tropisetron hydrochloride
A selective 5-HT3 serotonin receptor antagonist
What are the applications of Application
Tropisetron hydrochloride is a potent SR-3 antagonist
Definition
ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Biological Activity
Potent, orally active 5-HT 3 receptor antagonist. Antiemetic.
Biochem/physiol Actions
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
storage
Room temperature (desiccate)
Properties of Tropisetron hydrochloride
| Melting point: | 283-285°C |
| RTECS | NL6012520 |
| storage temp. | 2-8°C |
| solubility | H2O: >10mg/mL |
| form | solid |
| color | White to Light yellow |
| Water Solubility | Soluble in water |
| Merck | 14,9783 |
| InChI | InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?; |
| CAS DataBase Reference | 105826-92-4(CAS DataBase Reference) |
Safety information for Tropisetron hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P321:Specific treatment (see … on this label). P405:Store locked up. |
Computed Descriptors for Tropisetron hydrochloride
| InChIKey | ZAOQBEAHJFSJLY-NBVCILBMNA-N |
| SMILES | C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r| |
Tropisetron hydrochloride manufacturer
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, hydrochloride (1:1), (3-endo)-](https://img.chemicalbook.in/)
You may like
-
Tropisetron Hydrochloride CAS 105826-92-4View Details
105826-92-4 -
Tropisetron HCl 98% CAS 105826-92-4View Details
105826-92-4 -
Tropisetron hydrochloride CAS 105826-92-4View Details
105826-92-4 -
Tropisetron monohydrochloride CAS 105826-92-4View Details
105826-92-4 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.