Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
Synonym(s):3,3′,3′′-(4,4′,4′′-(Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))tris(propan-1-ol);THPTA
- CAS NO.：760952-88-3
- Empirical Formula: C18H30N10O3
- Molecular Weight: 434.51
- MDL number: MFCD27665386
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-22 17:12:53
What is Tris(3-hydroxypropyltriazolylMethyl)aMine 95%?
Description
THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction. THPTA is a superior alternative to water-insoluble TBTA. a) J. Am. Chem. Soc. 2011, 133, 17993. b) Bioconjugate Chem. 2010, 21, 1912.
The Uses of Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
Tris(3-hydroxypropyltriazolylmethyl)amine when complexed to copper(I) can be used as a catalyst.
storage
Store at -20°C
Properties of Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
| Melting point: | 331-336°C (decomposition) |
| Boiling point: | 723.8±70.0 °C(Predicted) |
| Density | 1.44±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly) |
| form | Solid |
| pka | 14.34±0.10(Predicted) |
| color | White to Off-White |
Safety information for Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
New Products
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