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HomeProduct name listTris(2-(2-methoxyethoxy)ethyl)amine

Tris(2-(2-methoxyethoxy)ethyl)amine

Synonym(s):TDA-1;Tris(3,6-dioxaheptyl)amine

  • CAS NO.:70384-51-9
  • Empirical Formula: C15H33NO6
  • Molecular Weight: 323.43
  • MDL number: MFCD00010748
  • EINECS: 274-590-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-21 18:25:24
Tris(2-(2-methoxyethoxy)ethyl)amine Structural

What is Tris(2-(2-methoxyethoxy)ethyl)amine?

Chemical properties

CLEAR PALE YELLOW TO BROWN LIQUID.
soluble in water, alcohol, ethers, and most organic solvents.

The Uses of Tris(2-(2-methoxyethoxy)ethyl)amine

Tris[2-(2-methoxyethoxy)ethyl]amine was used:

  • in oxidation of arylmethanols under phase-transfer conditions
  • as cryptand during phase-transfer glycosylation of 2-amino-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine
  • as phase-transfer catalyst in synthesis of 1,3-dideaza-2′-deoxyadenosine and related benzimidazole 2′-deoxyribonucleosides

Synthesis

Tris(2-(2-methoxyethoxy)ethyl)amine was prepared by the reaction of 2-(2-methoxy-ethoxy)ethanol with a mixture of ammonia gas and hydrogen gas in the presence of catalytic amounts of Raney nickel.

Properties of Tris(2-(2-methoxyethoxy)ethyl)amine

Melting point: <-100°C
Boiling point: 330 °C
Density  1.011 g/mL at 25 °C(lit.)
refractive index  n20/D 1.4486(lit.)
Flash point: >230 °F
storage temp.  Inert atmosphere,Room Temperature
form  Liquid
pka 6.92±0.50(Predicted)
color  Clear pale yellow to brown
Water Solubility  miscible
Sensitive  Air Sensitive & Hygroscopic
BRN  2369296
CAS DataBase Reference 70384-51-9(CAS DataBase Reference)
NIST Chemistry Reference Tris[2-(2-methoxyethoxy)ethyl]amine(70384-51-9)
EPA Substance Registry System Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]- (70384-51-9)

Safety information for Tris(2-(2-methoxyethoxy)ethyl)amine

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for Tris(2-(2-methoxyethoxy)ethyl)amine

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