Triphenyl phosphite

Chemical properties

Water-white to pale-yellow solid or oily liquid; pleasant odor. Combustible.

The Uses of Triphenyl phosphite

Triphenyl phosphite can be used:

• As a source of phosphorus and as a ligand for the synthesis of transition metal phosphide nanoparticles via heating-up process.
• To convert alcohols to alkyl halides.
• As a peptide coupling agent.
• As a low-temperature source of singlet oxygen after forming an adduct with ozone.
• To synthesize bromotriphenoxyphosphonium bromide, a brominating agent, by reacting with bromine.

The Uses of Triphenyl phosphite

Chemical intermediate, stabilizer systems for resins, metal scavenger, diluent for epoxy resins.

The Uses of Triphenyl phosphite

Stabilizer/antioxidant for vinyl plastics and polyethylene, polypropylene, styrene copolymers, and rubber.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Organophosphates, such as Triphenyl phosphite, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Health Hazard

Triphenyl phosphite (TPP) is a skin irritant and sensitizer in humans and is neurotoxic in laboratory animals.Systemic effects have not been reported in humans.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. An experimental eye and severe human skin irritant. Combustible when exposed to heat or flame. To fight fire, use CO2, mist, dry chemical. When heated to decomposition it emits toxic fumes of POx. See also PHENOL.

Purification Methods

Its ethereal solution is washed succesively with aqueous 5% NaOH, distilled water and saturated aqueous NaCl, then dried with Na2SO4 and distilled under vacuum after evaporating the diethyl ether. [Walsh J Am Chem Soc 81 3023 1959, Verkade & Coskren in Organo Phosphorus Compounds (Kosolapoff & Maier eds) Wiley Vol 6 pp 211-577 1973, Beilstein 6 IV 695.]