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HomeProduct name listTrimebutine maleate

Trimebutine maleate

Synonym(s):3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester;Trimebutine maleate salt

  • CAS NO.:34140-59-5
  • Empirical Formula: C26H33NO9
  • Molecular Weight: 503.54
  • MDL number: MFCD00133874
  • EINECS: 251-845-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 08:26:49
Trimebutine maleate Structural

What is Trimebutine maleate?

Chemical properties

White Solid

The Uses of Trimebutine maleate

Opioid receptor agonist. Antispasmodic

The Uses of Trimebutine maleate

Trimebutine maleate is an antispasmodic that functions as an opioid receptor agonist. Its mechanism of action involves regulating bowel movements and enhancing gastrointestinal function. Trimebutine is commonly used in the treatment of Irritable bowel syndrome. It is also used to restart the movement of the gut after abdominal surgery and to prevent intestinal blockage (paralytic ileus).

What are the applications of Application

Trimebutine maleate is a gastrointestinal antispasmotic

Definition

ChEBI: Trimebutine maleate is a trihydroxybenzoic acid that is proposed as a spasmolytic with possible local anesthetic action for the treatment of gastrointestinal disorders.

Side Effects

Possible side effects of trimebutine may include dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness, indigestion, or headache. Other less frequent side effects are difficulty urinating, hearing loss, or painful breast enlargement. If any of these symptoms persist or worsen, please inform your doctor or pharmacist immediately.

References

https://www.drugs.com/medical-answers/trimebutine-3571789/
Trimebutine: abuse, addiction and overdose
https://myhealth.alberta.ca/Health/medications/Pages/conditions.aspx?hwid=fdb8090

Properties of Trimebutine maleate

Melting point: 122-124°C
storage temp.  2-8°C
solubility  Slightly soluble in water, soluble in acetonitrile, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent).
form  neat
form  Solid
color  White
CAS DataBase Reference 34140-59-5(CAS DataBase Reference)

Safety information for Trimebutine maleate

Computed Descriptors for Trimebutine maleate

InChIKey FSRLGULMGJGKGI-BTJKTKAUSA-N

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