Trimebutine maleate
Synonym(s):3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester;Trimebutine maleate salt
- CAS NO.：34140-59-5
- Empirical Formula: C26H33NO9
- Molecular Weight: 503.54
- MDL number: MFCD00133874
- EINECS: 251-845-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is Trimebutine maleate?
Chemical properties
White Solid
The Uses of Trimebutine maleate
Opioid receptor agonist. Antispasmodic
The Uses of Trimebutine maleate
Trimebutine maleate is an antispasmodic that functions as an opioid receptor agonist. Its mechanism of action involves regulating bowel movements and enhancing gastrointestinal function. Trimebutine is commonly used in the treatment of Irritable bowel syndrome. It is also used to restart the movement of the gut after abdominal surgery and to prevent intestinal blockage (paralytic ileus).
What are the applications of Application
Trimebutine maleate is a gastrointestinal antispasmotic
Definition
ChEBI: Trimebutine maleate is a trihydroxybenzoic acid that is proposed as a spasmolytic with possible local anesthetic action for the treatment of gastrointestinal disorders.
Side Effects
Possible side effects of trimebutine may include dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness, indigestion, or headache. Other less frequent side effects are difficulty urinating, hearing loss, or painful breast enlargement. If any of these symptoms persist or worsen, please inform your doctor or pharmacist immediately.
References
https://www.drugs.com/medical-answers/trimebutine-3571789/
Trimebutine: abuse, addiction and overdose
https://myhealth.alberta.ca/Health/medications/Pages/conditions.aspx?hwid=fdb8090
Properties of Trimebutine maleate
| Melting point: | 122-124°C |
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water, soluble in acetonitrile, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent). |
| form | neat |
| form | Solid |
| color | White |
| CAS DataBase Reference | 34140-59-5(CAS DataBase Reference) |
Safety information for Trimebutine maleate
Computed Descriptors for Trimebutine maleate
| InChIKey | FSRLGULMGJGKGI-BTJKTKAUSA-N |
Trimebutine maleate manufacturer
BDR Pharmaceuticals International Pvt Ltd
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